Botany JoVE (Open Access) Citable · DOI

Implantation of the Syncardia Total Artificial Heart

Name: Implantation of the Syncardia Total Artificial Heart
Uploaded: 2026-08-05
Duration: 16 min 11 s
Description: With advances in technology, the use of mechanical circulatory support devices for end stage heart failure has rapidly increased. The vast majority of ...

DOI: 10.3791/50377-v

What you'll learn

✓ Identify indications for total artificial heart implantation
✓ Prepare the Syncardia device for surgical implantation
✓ Execute operative implantation and cannulation techniques
✓ Manage cardiopulmonary bypass initiation and patient outcomes

Protocol

Biopharma Insights The purpose of this manuscript is to briefly review indications, management, and outcomes for the total artificial heart. Video operative techniques for device implantation are presented.

Difficulty

advanced

Total time

~4-6 hrs/procedure

Model organism

Human patient (bovine/ovine preclinical models also used)

Biosafety

BSL-2

Steps

Review patient case and indications

Present patient history, indications, and contraindications for total artificial heart implantation.

▶ 01:27

Prepare the Syncardia device

Inspect and set up the total artificial heart device and required surgical instruments.

▶ 03:08

Begin device implantation

Initiate surgical implantation of the artificial heart into the chest cavity.

▶ 04:01

Cannulate and start cardiopulmonary bypass

Cannulate great vessels and initiate cardiopulmonary bypass to support circulation.

▶ 04:51

Review operative results and outcomes

Examine postoperative results, device performance, and patient outcomes.

▶ 13:53

Summarize conclusions and management

Conclude with key takeaways on management and outcomes for the total artificial heart.

▶ 15:37

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